MOUSE LINES
SignR3 is one of five murine equivalents of human DcSign (Dendritic cell-specific ICAM-3 [intracellular adhesion molecule-3] grabbing non-integrin). It is localized on mouse chromosome 8 in a cluster with three other related genes: SignR1, SignR2 and SignR4, and in the vicinity of mouse DcSign.
SignR3 is a C-type lectin expressed at low levels in different mouse tissues, most notably in skeletal muscle and spleen.
